Endocrine Research Updates

For Medical Professionals

microscope, dna double helix and human cell
The ThyroSeq v2.1 multigene next generation sequencing test showed a high sensitivity and specificity in the detection of cancer in thyroid nodules with atypia of undetermined significance/follicular lesion of undermined significance (AUS/FLUS) cytology.
Elderly Woman Reading Warning Labels on Pill Bottles
The U.S. Food and Drug Administration added warnings about diabetic ketoacidosis and serious urinary tract infections to labels of all SGLT2 inhibitors in December, 2015.
Slowing progression of prediabetes appears to occur as a side benefit of Viagra.
Men with prediabetes may experience improved insulin sensitivity when prescribed Viagra.
Three-month treatment with sildenafil improved insulin sensitivity in patients with prediabetes and also reduced levels of biological markers of kidney and heart disease (ie, albumin and creatinine).
question marks, colorful blocks
Shared-decision making and use of a surveillance protocol is central to management of patients with differentiated thyroid cancer who prefer ongoing surveillance over biopsy or surgery.
Adults with type 2 diabetes have a 15% greater risk for death from any cause compared to the general population, which is a historically low level.
normal eye and diabetic retinopathy
Ranibizumab blocks the effects of vascular endothelial growth factor (VEGF) and is indicated for the treatment of wet age-related macular degeneration, macular edema following retinal vein occlusion, and diabetic macular edema.
Weight loss concept woman smiling
Highlight from ObesityWeek 2015
Even as experts continue to wrestle with the optimal methods of weight loss, whether surgical or nonsurgical, they're also focusing on the best ways to maintain the weight loss.
brain thinking about eating, exercise, lifestyle choices
Highlight from ObesityWeek 2015
Borrowing a technique from addiction specialists, obesity specialists find motivational interviewing helps weight loss patients.
overweight woman eating at night
Highlight from ObesityWeek 2015
Early lapses on a weight loss program predict overall weight loss success, even if weight loss on track, study finds. Acceptance-based treatment beats standard treatment.
bandaged foot, diabetic foot infection
New data from a retrospective cohort study show that the incidence of diabetic foot infections has decreased markedly—by 52%—between 1996 and 2010, according to a report in the American Journal of Infection Control.
Bariatric surgery, vertical sleeve gastrectomy
Three years after undergoing bariatric surgery, adolescents experienced major improvements in their weight, metabolic health, and quality of life, according to findings from the prospective, NIH sponsored Teen-LABS (Longitudinal Assessment of Bariatric Surgery) study.
alcoholic beverages
New findings from a large prospective cohort add support to the hypothesis that moderate alcohol consumption may lower the risk of papillary and follicular thyroid carcinomas.
Highlight from ObesityWeek 2015
While speaking at ObesityWeek 2015, Daniel Bessesen, MD proposed a new paradigm, thinking of prescription weight loss medicines as a treatment for a chronic condition—obesity—similar to how physicians treat hypertension, hyperlipidemia and diabetes.
Highlight from ObesityWeek 2015
Overweight and obesity increase the risk of multiple forms of cancer, yet patients remain largely unaware of the association, according to experts speaking at ObesityWeek 2015 in Los Angeles.
Pharmacist filling a prescription
It is unclear whether antibiotics are directly linked to type 2 diabetes or if patients requiring repeated antibiotic use have undiagnosed diabetes, placing them at increased risk of infections.
Prescription Medicine Bottles
Nearly 40% of elderly use 5 or more medications
Overall prescription drug use increased 9% among U.S. adults between 1999 and 2012, according to data from the National Health and Nutrition Examination Survey.
Dental X-Ray
While exposure to the standard therapy for XLH has no apparent benefit on enthesopathy, there is some benefit to oral health in adults.
Exposure to standard therapeutic regimen for X-linked hypophosphatemia (XLH) of calcitriol and phosphate has no effect on enthesopathy but is protective of dental health.
Overweight, obese female, knees bent, on scale weighing herself
Mechanisms related to excessive weight gain have a deleterious effect on the development and management of osteoarthritis (OA).
Obesity is a long-known major risk factor for osteoarthritis. Now, scientists are uncovering new information about just how risky excess weight is for joints. They're also discovering other mechanisms besides obesity that may drive risk.
Side view of the human brain and prefrontal cortex
Neuromodulation targeting the dorsolateral prefrontal cortex (LDLPFC) decreased calorie consumption and increased weight loss in adults with obesity, according to a recent study.
measuring an overweight man's waist size using a measuring tape
Highlight from ObesityWeek 2015
During ObesityWeek 2015, Melissa Crane, PhD explained men aren't attracted to typical weight loss programs, viewing them as complicated and tailored to women. They want simplified weight loss programs and want to lose weight for health reasons.