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Endocrine Research Updates

For Medical Professionals

microscope, dna double helix and human cell
Thyroid cancer
ThyroSeq Assay Shows High Sensitivity and Specificity in Detecting Thyroid Cancer
The ThyroSeq v2.1 multigene next generation sequencing test showed a high sensitivity and specificity in the detection of cancer in thyroid nodules with atypia of undetermined significance/follicular lesion of undermined significance (AUS/FLUS) cytology.
Elderly Woman Reading Warning Labels on Pill Bottles
Diabetes complications
FDA Adds Ketoacidosis and Urinary Tract Infection Warnings to SGLT2 Inhibitor Labeling
The U.S. Food and Drug Administration added warnings about diabetic ketoacidosis and serious urinary tract infections to labels of all SGLT2 inhibitors in December, 2015.
Slowing progression of prediabetes appears to occur as a side benefit of Viagra.
Pre-Diabetes
Viagra Improves Insulin Sensitivity in People with Prediabetes
Men with prediabetes may experience improved insulin sensitivity when prescribed Viagra.
Three-month treatment with sildenafil improved insulin sensitivity in patients with prediabetes and also reduced levels of biological markers of kidney and heart disease (ie, albumin and creatinine).
question marks, colorful blocks
Thyroid nodules
Ethical Considerations for Continued Observation of Thyroid Lesions
Shared-decision making and use of a surveillance protocol is central to management of patients with differentiated thyroid cancer who prefer ongoing surveillance over biopsy or surgery.
researches
Diabetes complications
Risk of Death from Type 2 Diabetes Is at a Historically Low Level
Adults with type 2 diabetes have a 15% greater risk for death from any cause compared to the general population, which is a historically low level.
normal eye and diabetic retinopathy
Diabetes complications
Ranibizumab (Lucentis) Found Noninferior to Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy
Ranibizumab blocks the effects of vascular endothelial growth factor (VEGF) and is indicated for the treatment of wet age-related macular degeneration, macular edema following retinal vein occlusion, and diabetic macular edema.
Weight loss concept woman smiling
Obesity
What Works for Weight Loss Maintenance?
Highlight from ObesityWeek 2015
Even as experts continue to wrestle with the optimal methods of weight loss, whether surgical or nonsurgical, they're also focusing on the best ways to maintain the weight loss.
brain thinking about eating, exercise, lifestyle choices
Obesity
Motivational Interviewing: Key to Inspiring Weight Loss?
Highlight from ObesityWeek 2015
Borrowing a technique from addiction specialists, obesity specialists find motivational interviewing helps weight loss patients.
overweight woman eating at night
Obesity
New Clues About Weight Loss Success
Highlight from ObesityWeek 2015
Early lapses on a weight loss program predict overall weight loss success, even if weight loss on track, study finds. Acceptance-based treatment beats standard treatment.
bandaged foot, diabetic foot infection
Diabetes complications
Incidence of Diabetic Foot Infections Decreased by Half from 1996 to 2010
New data from a retrospective cohort study show that the incidence of diabetic foot infections has decreased markedly—by 52%—between 1996 and 2010, according to a report in the American Journal of Infection Control.
Bariatric surgery, vertical sleeve gastrectomy
Obesity
Adolescent Bariatric Surgery Reverses Type 2 Diabetes in Nearly All Teens in Recent Study
Three years after undergoing bariatric surgery, adolescents experienced major improvements in their weight, metabolic health, and quality of life, according to findings from the prospective, NIH sponsored Teen-LABS (Longitudinal Assessment of Bariatric Surgery) study.
alcoholic beverages
Thyroid cancer
Moderate Alcohol Consumption May Lower the Risk for Thyroid Cancer
New findings from a large prospective cohort add support to the hypothesis that moderate alcohol consumption may lower the risk of papillary and follicular thyroid carcinomas.
obese,overweight,medication
Obesity
Prescription Weight Loss Drugs: Patients Want, But Not Long-Term
Highlight from ObesityWeek 2015
While speaking at ObesityWeek 2015, Daniel Bessesen, MD proposed a new paradigm, thinking of prescription weight loss medicines as a treatment for a chronic condition—obesity—similar to how physicians treat hypertension, hyperlipidemia and diabetes.
Obesity,overweight,complications
Obesity
Obesity, Cancer: Evidence Grows Supporting the Link
Highlight from ObesityWeek 2015
Overweight and obesity increase the risk of multiple forms of cancer, yet patients remain largely unaware of the association, according to experts speaking at ObesityWeek 2015 in Los Angeles.
Pharmacist filling a prescription
Type 2 Diabetes
Recurrent Antibiotic Use Linked to Risk of Type 2 Diabetes
It is unclear whether antibiotics are directly linked to type 2 diabetes or if patients requiring repeated antibiotic use have undiagnosed diabetes, placing them at increased risk of infections.
Prescription Medicine Bottles
Other Endocrine Disorders
Increases in Prescription Drug Use and Polypharmacy Found in Past Decade
Nearly 40% of elderly use 5 or more medications
Overall prescription drug use increased 9% among U.S. adults between 1999 and 2012, according to data from the National Health and Nutrition Examination Survey.
Dental X-Ray
Other Endocrine Disorders
Treatment of X-linked hypophosphatemia in Adults May Prevent Dental Disease
While exposure to the standard therapy for XLH has no apparent benefit on enthesopathy, there is some benefit to oral health in adults.
Exposure to standard therapeutic regimen for X-linked hypophosphatemia (XLH) of calcitriol and phosphate has no effect on enthesopathy but is protective of dental health.
Overweight, obese female, knees bent, on scale weighing herself
Obesity
Osteoarthritis and Obesity: Anticipated Comorbidities with New Clues to Care
Mechanisms related to excessive weight gain have a deleterious effect on the development and management of osteoarthritis (OA).
Obesity is a long-known major risk factor for osteoarthritis. Now, scientists are uncovering new information about just how risky excess weight is for joints. They're also discovering other mechanisms besides obesity that may drive risk.
Side view of the human brain and prefrontal cortex
Obesity
Neuromodulation Shows Promise in the Treatment of Obesity
Neuromodulation targeting the dorsolateral prefrontal cortex (LDLPFC) decreased calorie consumption and increased weight loss in adults with obesity, according to a recent study.
measuring an overweight man's waist size using a measuring tape
Obesity
Do Men Need Different Weight Loss Programs?
Highlight from ObesityWeek 2015
During ObesityWeek 2015, Melissa Crane, PhD explained men aren't attracted to typical weight loss programs, viewing them as complicated and tailored to women. They want simplified weight loss programs and want to lose weight for health reasons.
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