Endocrine Research Updates

For Medical Professionals

Understanding of bone response to dual drugs informs osteoporosis management.
Bone density changes were favorable with dual therapy using teriparatide and abaloparatide
Older adults with type 2 diabetes benefit from triple drug treatment.
Data is accruing to challenge current recommendations to provide less aggressive treatment to lower hemoglobin A1c levels in people over age 65 years in favor of combination therapy.
Researchers discovered a way to promote beta cell proliferation in diabetics..
Researchers from the Icahn School of Medicine at Mount Sinai achieved significant beta cell proliferation using a combination of pharmacologic and genetic inhibition.
Thyroid cancer patients respond just as well to low dose RAI as with high dose.
Low-dose radioactive iodine ablation yields similar recurrence rates for thyroid cancer patients followed for five years.
Is there a link between poor thyroid function and fatty liver disease?
Given the rising rates of nonalcoholic fatty liver disease, and the comorbidity of cardiovascular disease, a team from Stanford examined the connection between low thyroid function and fibrosis
Subtypes of obesity may aid clinicians in predicting responsiveness to surgery.
Researchers classified individuals into four subtypes of obesity to assess who might achieve sustained weight loss after gastric bypass surgery.
Prevention gains urgency in 2019 diabetes recommendations.
The need to step-up efforts to prevent progression of diabetes, and to place patients front and center in their own care are featured prominently in the newly revised edition of the American Diabetes Association Standards of Medical Care in Diabetes.
People with type 1 diabetes are at increased for Addison's disease, too.
For the first time, predictive clinical signs of Addison's disease have been identified in people with type 1 diabetes, making an earlier diagnosis possible.
Need to treatment people with type 2 diabetes for reduce heart disease risk too.
An American College of Cardiology expert statement advises clinicians to take a more concerted, consistent effort in achieving cardiovascular risk reduction in patients with both type 2 diabetes and atherosclerosis.
Using tablets (iPads) makes medical data readily available.
When clinicians encourage patients to utilize digital and online health technology and employ these
Patients are likely to present with multiple autoimmune disorders.
The prevalence of polyautoimmunity in people with Graves’ disease, and the rise of Multiple Autoimmune Syndrome in patients with endocrine disorders require greater diagnostic and management investment.
Common conditions like sleep apnea arise frequently in people with acromegaly.
Sex differences in symptoms and early manifestations recognized by patients before clinicians, and identification and screening for common comorbidities still lacking despite published guidelines.
Experts questions validity of copeptin over water-deprivation testing.
Might blood testing for copeptin offer an easier diagnostic method than the customary water-deprivation in assessing for diabetes insipidus? The researchers recommend copeptin as the new gold standard but longtime experts express caution.
Buyer beware: Nutritional supplements may include toxic substances.
Be prepared to caution patients of the undesirable health consequences possible from banned, potentially dangerous pharmaceuticals, and other undisclosed ingredients in so-called natural, nutritional supplements.
ADA prioritizes access to affordable ongoing diabetes patient education.
In an ADA/EASD consensus report on type 2 diabetes treatment, involving patients in their care is the best way forward in achieving optimal blood glucose control, better outcomes, and reducing complications.
Testosterone replacement therapy may be beneficial in men with COPD.
Testosterone replacement therapy may be warranted to reduce hospitalizations for chronic obstructive pulmonary disease.
Watiing for diagnosis of osteoporosis may put older women at risk for death.
Post-menopausal women who do not meet the definition of osteoporosis may be candidates for earlier intervention with bisphosphonate therapy.
People with higher risk for diabetes complications need more aggressive therapy.
STOP Diabetes trial results suggest significant benefits in patients deemed at higher risk for type 2 diabetes who receive more aggressive pharmacotherapy, against lifestyle and metformin to reverse diabetes and associated complications.
Adding locaserin may improve reduce heart disease, obesity and diabetes.
Brief news features on recently released FDA approvals and preliminary clinical trials results for the weight loss drug locaserin, a diabetes combination therapy, and inhaled insulin.
New study supports first effective treatment for cardiomyopathy in diabetes.
Researchers say tafamidis may also slow cognitive functional decline; findings were lauded by an independent expert who called cardiovascular benefits ''substantial."
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