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Endocrine Research Updates

For Medical Professionals

Professional with blue gloves handling medicine in a pharmacy lab
Comments by Study Co-Lead Author, Pieter Gillard, PhD and Elbert Huang, MD, MPH, FACP
Marked differences in 5-year survival rates were found among patients with diabetes based on the type of glucose-lowering agent they were prescribed.
thyroid pictured as a puzzle, surgeon's hands
Commentary by Lead Author Mingzhao Xing, MD, PhD and Thomas J. Giordano, MD, PhD
Patients with follicular-variant papillary thyroid cancer overall have the least aggressive form of this disease, compared with patients with conventional PTC and tall-cell PTC variants.
thyroid ultrasonography
Commentary by Senior Author R. Michael Tuttle, MD and John C. Morris, III, MD
A risk-stratified clinical decision-making framework may provide clinicians with a tool to identify which patients are most likely to benefit from an active surveillance management approach for papillary microcarcinoma.
uterine fibroids
Commentary by Jason Y.Y. Wong, ScD; Jennifer S. Lee, MD, PhD; Richard S. Legro, MD
Women who have high levels of both testosterone and estrogen in midlife may be at greater risk of developing uterine fibroids than women with low levels of these hormones, according to a 13-year epidemiologic study published in the Journal of Clinical Endocrinology & Metabolism.
Female doctor with  male peers in background
Commentary by Elaine Pelley, MD and Julianne Imperato-McGinley, MD
Endocrinology is predicted to become a female-predominant specialty over the next several decades, according to a literature review in the January issue of The Journal of Clinical Endocrinology and Metabolism.
Depressed man
Commentary by Jay A. Brieler, MD and Jennifer Frost, MD
Depression is not only a disease of emotions and behavior. Depression is a risk factor for vascular disease, diabetes, and worse outcomes after heart surgery. Proper treatment of depression is important for many aspects of a patient's health.
Kidney disease
The prevalence of diabetes rose among commercially-insured children and adolescents between 2002 to 2013, according to a study published online ahead of print in Diabetes Care. The study also showed that while diabetic nephropathy is relatively uncommon in youth, the prevalence also is on the rise.
Patient in the dentist's chair in front of monitor
Commentary by Coauthor Bei Wu, PhD; and Edmond R. Hewlett, DDS — Spokesperson from the American Dental Association and Professor, Section of Restorative Dentistry & Associate Dean of Outreach and Diversity, UCLA School of Dentistry
Adults with diabetes have a twofold higher risk for tooth loss than adults who do not have diabetes, according to findings from a longitudinal analysis of data from the 1971-2012 National Health and Nutrition Examination Survey.
Woman holding her neck
The diabetic group had a higher mean number of doctor visits for musculoskeletal pain in the neck and shoulders, limbs, lumbar spine, back and pelvis compared with the nondiabetic group. In both groups, the most common locations of musculoskeletal pain necessitating doctor visits were pain in the lumbar spine, back and pelvis.
Pregnant Girl Looking into Refrigerator
Pregnancy in adolescents with type 2 diabetes was linked to miscarriage, stillbirth or intrauterine death in 26% of pregnancies and major congenital anomaly in 21% of live-born infants in the randomized controlled Treatment Options for type 2 Diabetes in Adolescents and Youth (TODAY) study.
Glycemic Index Tabs
Researchers have developed a diabetes algorithm to supplement clinical decision-making when establishing glycemic goals for patients with type 2 diabetes, according to a study reported in the December issue of Diabetes Care.
white and pink oral medications, pills
The U.S. Food and Drug Administration (FDA) announced that it has eliminated the Risk Evaluation and Mitigation Strategy (REMS) for rosiglitazone-containing type 2 diabetes medicines (ie, Avandia, Avandamet, Avandaryl, and generics).
bariatric surgery, gastric bypass
Predictors of diabetes remission varied by type of bariatric surgery, according to a study published online ahead of print in Diabetes Care. The relationship between bariatric surgery and diabetes remission appears to be independent of baseline BMI, the study authors reported.
Research Keypad
In patients with type 2 diabetes and acute coronary syndrome, treatment with the glucagon-like peptide 1 (receptor agonist lixisenatide did not increase or decrease the rate of cardiovascular events or other serious adverse events, according to results of the Evaluation of Lixisenatide in the Acute Coronary Syndrome (ELIXA) trial.
3d rendered illustration of the male thyroid gland - cancer
Review of diagnostic slides from cases of follicular thyroid carcinoma diagnosed over the past 50 years resulted in reclassification of nearly three-fourths of cases, according to a study in the journal of Thyroid.
microscope, dna double helix and human cell
The ThyroSeq v2.1 multigene next generation sequencing test showed a high sensitivity and specificity in the detection of cancer in thyroid nodules with atypia of undetermined significance/follicular lesion of undermined significance (AUS/FLUS) cytology.
Elderly Woman Reading Warning Labels on Pill Bottles
The U.S. Food and Drug Administration added warnings about diabetic ketoacidosis and serious urinary tract infections to labels of all SGLT2 inhibitors in December, 2015.
Three-month treatment with sildenafil improved insulin sensitivity in patients with prediabetes and also reduced levels of biological markers of kidney and heart disease (ie, albumin and creatinine).
question marks, colorful blocks
Shared-decision making and use of a surveillance protocol is central to management of patients with differentiated thyroid cancer who prefer ongoing surveillance over biopsy or surgery.
researches
Adults with type 2 diabetes have a 15% greater risk for death from any cause compared to the general population, which is a historically low level.
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