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Endocrine Research Updates

For Medical Professionals

Clinical training and sensitivity to transgender patients needs improvement.
Lack of training for gender-affirming patients identifid; medical interventions, while not complex, require more than simply giving estrogen or testosterone.
Autotaxin, a spinal fluid enzyme, may predict risk of Alzheimers, Diabetes.
Evaluating levels of autotaxin, an enzyme found in the fluid around the brain and spine, may be useful in identifying those at risk of cognitive decline and type 2 diabetes, Iowa researchers find.
The 2016 guidelines, issued after 6 years of new evidence and experience, offer more targeted recommendations for clinical management of women who have thyroid disease once they become pregnant as well as postpartum. Four key changes in the new guidelines are highlighted.
Elevating the predictive accuracy of biopsy node assessment may be possible using both a highly specific oncogene panel and a classification test for miRNA gene expression to improve surgical decision-making.
Improving sleep by adjusting work-shifts to fit a person's chronotype may be the most effective approach to address resistant diabetes or creeping obesity.
To provide the most effective care for patients with diabetes, EndocrineWeb editorial board members consider the barriers to care from individualized care planning and a change to prevention over fee-for-serve care, to integrating obesity strategies into diabetes management.
When surgery is not an option, thiazide diuretics--an old drug class with complicated side effects--may offer an effective alternative for some patients.
Annual review of standards has many firsts, including the need to individualize treatment with a focus on staging diabetes; addressing obesity, sleep, mental health; and, accounting for patient costs in treatment to achieve the best outcomes for people at risk of or having diabetes.
Cannabis is known to have a positive role in reducing pain but its effect on metabolism and the endocrine system appear less favorable. Researchers examined the use of cannabis in thyroid function, finding a significantly elevated TSH among current users who were typically young males whose risk of thyroid or diabetes is low.
With 9 endpoints of gastric, metabolic and bariatric surgeries identified, clinicians will have targeted results to utilize in guiding patients in the selection or avoidance of invasive weight loss procedures.
In promoting a patient-centered approach to diabetes care, endocrinologists are urged to assess mental state of patients as a means to better outcomes.
Draft guidelines unveiled to foster better assessment of fracture risk, and more aggressive strategies for preventing/treating osteoporosis for the 30-50 percent of patients on glucocorticoid therapy
Clinicians may have clear markers to guide prescribing decisions with regard to those at highest risk of developing diabetes—a risk that appears to be very low for most, but not all.
Clinicians have 2 clear markers that may predict who's at highest risk of developing diabetes:
Clinicians should follow women who develop gestational diabetes and intervene early to reduce risk for cardiovascular diseases.
Clinical Practice for Iodine Supplementation during Preconception, Pregnancy, and Lactation Lags Behind Medical Society Recommendations
Iodine supplementation for women of childbearing age, pregnancy and breastfeeding is recommended but 3 in 4 practitioners do not followed the prescribed recommendations.
Non-Invasive Imaging may reduce need for removal of benign thyroid nodules.
Using FDG-PET in combination with sonographic features may improve diagnosis of indeterminate thyroid nodules that are benign, aiming for fewer surgeries.
Researchers found that Sitagliptin and Metformin therapy may prevent hyperglycemic relapses in obese African Americans
Treatment with pioglitazone, a thiazolidinedione, acts as a preventive agent in individuals with insulin sensitivity who are at elevated risk for cardiovascular disease.
Results may needlessly worry some, researcher says; others call it an urgent need to alert Americans early and get them the medical care necessary to avoid costly care later
Despite the need, new weight loss medications remain underutilized and inadequately prescribed
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