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Endocrine Research Updates

For Medical Professionals

Man hanging on the lower end of a gauge, lower risk
Overweight diabetic patients who undergo gastric bypass surgery reduced their 10-year risk of having a heart attack by 40% and their risk for suffering a stroke by 42%.
Diabetes is better cut-off for weight-loss surgery than body mass index (BMI)
Diabetes poses the highest risk for mortality from obesity, and should be considered when deciding who should have bariatric weight-loss surgery
Group Visits Are Cost-Effective Way to Improve Glycemic Control
Shared medical appointments are now being used to allow for more comprehensive diabetes care as well as social support, with the latest research showing significant improvements in glycemic control.
Higher Magnesium Intake May Lower Risk for Type 2 Diabetes
In a study involving more than 2,500 people, those with the highest magnesium intake had the lowest risk of developing type 2 diabetes over a 7-year period.
DPP-4 Inhibitor Onglyza (saxagliptin) Does Not Increase Heart Disease Risks
Large study shows no increased risk of myocardial infarction (heart attach), ischemic strokes, and death in over 16,000 patients treated with saxagliptin (Onglyza).
American Diabetes Association (ADA) New Guidelines Stress Individualized Meal Planning That Fits a Diabetics Food Preference and Lifestyle
Report stresses individualized meal planning that fits a person's food preferences and lifestyle.
Depressed patients have increased risk for diabetes
Antidepressants appeared to be associated with an increased risk for diabetes. However, it is unclear whether this is a causal relationship and the magnitude of the effect may be small.
woman getting ultrasound of a thyroid from doctor
List contains common tests to avoid as well as tests patients with diabetes really should be conducting.
The Endocrine Society and the American Association of Clinical Endocrinologists (AACE) released a list of specific tests or procedures that are commonly ordered but not always necessary in endocrinology.
Groups sought to standardize care
AACE, ACE, and TOS published clinical practice guidelines to teach healthy eating in order to prevent and manage endocrine and metabolic disorders.
Improvement in quality of care seen
Use of an outpatient electronic health record at Kaiser Permanente Northern California was associated with significant decreases in emergency department visits and hospitalizations among patients with diabetes.
Dysglycemia and peripheral neuropathy seen
Fluoroquinolones have been linked to increased risks of dysglycemia in patients with diabetes and peripheral neuropathy in diabetic and non-diabetes patients.
Greater psoriasis severity was associated with greater disease burden
Psoriasis is linked to a 22% increased risk for type 2 diabetes as well as a greater prevalence of other systemic comorbidities.
Weight loss reduces risk of developing type 2 diabetes by 85%
Patients who lose 10% of their body weight within 6 months of diagnosis of pre-diabetes may reduce their risk of developing type 2 diabetes by 85% over the next 3 years.
Twenty-five percent decreased risk for cancer-related deaths seen

Cumulative exposure to metformin after prostate cancer diagnosis was linked to a nearly 25% decreased risk for cancer-related mortality in men with diabetes.

Microvascular disease in the kidney is paralleled by microvascular disease in the brain

Cognitive decline in patients with diabetes may be associated with microvascular changes in the kidneys, leading to microvascular changes in the brain, a new research study suggests.

Diabetic foot ulcers debridement should be part of the standard of care, and repetitive weekly debridement may be beneficial

Frequent debridement of chronic wounds is associated with improved healing, according to James Wilcox, RN, lead author of a retrospective study of more than 300,000 wounds.

Patients with type 2 diabetes who are taking glucose-lowering medications are at risk for severe hypoglycemia regardless of whether their diabetes is poorly or well controlled

Patients with type 2 diabetes who are taking glucose-lowering medications are at risk for severe hypoglycemia regardless of whether their diabetes is poorly or well controlled, according to data fr

Insufficient evidence of cancer link seen
There is currently insufficient evidence to support a definitive link between antihyperglycemic medications and cancer development, according to a consensus statement released by the American Association of Clinical Endocrinologists (AACE).
Weight loss, exercise, and some supplements can help lower inflammation, reducing risks of heart disease, cancer and diabetes

Many patients with diabetes take complementary and alternative (CAM) therapies—some to lessen the number of diabetes agents they need and others to treat comorbidities such as peripheral neuropathy

Taskforce finds current screening recommendations missed detecting more than 50% of diabetes cases
The US Preventive Services Task Force (USPSTF) screening recommendations missed detecting more than 50% of cases of undiagnosed diabetes.
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