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Endocrine Research Updates

For Medical Professionals

Possible pathway to unrepress beta cells may lead to cure for diabetes.
Analyses of insulinomas provide pathway to pharmacologically target genes and gene families that may restore function of beta cells in individuals with type 1 and type 2 diabetes.
The lower the LDL the better with a combination of a statin and PSK9-inhibitor.
A secondary analysis of the Fourier study findings indicates that patients with the lowest LDL had best cardiovascular outcomes.
Delivering the right health messages will prompt best medical outcomes.
Giving patients the right number of health messages may matter, but best outcomes will depend on the content, timing, and receptiveness of the patient.
Responses to food differ significantly in individuals sensitive to insulin vs. t
Findings suggest that central insulin plays a direct role in individuals who are insulin sensitive vs insulin resistant, offering promise of improved understanding of food intake regulation in people with prediabetes or who are obese but not yet diabetic.
The American Diabetes Association updated the 2003 guidelines to incorporate advances in research to on how best to treat high blood pressure in patients with diabetes.
Researchers advanced the understanding of how glucose metabolism in platelets that could help explain the increased risk of clotting in people with diabetes.
Online game proves effective in improving care in patients with type 2 diabetes.
Diabetes self-management education delivered via an online game reduced hemoglobin A1c levels in patients with type 2 diabetes.
Exploring the best treatment for Grave's disease.
A research team attempted to make a case for antithyroid medications as the most efficacy and desirable therapy for Grave's disease, but at least 1 US expert refuted the data.
Hormone therapy for prostate cancer may improve bone mineral density.
Osteoporosis medications may be necessary to improve bone integrity and reduce fracture risk in men with prostate cancer who undergo androgen-deprivation therapy.
Genetic mutation leads to a rare form of male infertility.
Researchers have identified a gene mutation that appears to inhibit sperm formation, leading to a cause of failed sperm production.
Seniors with diabetes at 17-fold increased risk for falls.
Individuals with diabetes require greater vigilance from clinicians to elicit lifestyle changes aimed at reducing risk for future falls, a challenge that will increase with age.
Do we need legislation to designate September as PCOS month?
While the National Polycystic Ovary Syndrome Association seeks to raise attention for PCOS, their efforts are not aligned with a recent NIH report on the condition.
Cornell researchers offer insight into bone changes behind atypical fractures.
Researchers offer clearer understanding of the changes that occur in bone structure following treatment with bisphosphonates that may be behind the rare, atypical fractures.
Alzheimer's drug improves insulin response and reduces inflammation in obesity.
A medication used to treat dementia demonstrated anti-inflammatory action that improved insulin sensitivity and other markers of inflammation in obese patients.
Medication used to treat Alzheimer's disease improves insulin sensitivity and markers of inflammation in metabolic syndrome.
People with significant visceral fat may benefit from anti-inflammatory therapy.
The anti-inflammatory asthma and allergy medication, amlexanox, significantly reduced HbA1c, CRP, insulin resistance, and fatty liver in a subset of people with type 2 diabetes.
A healthy lIfestyle can reduce the risk of diabetes and osteoporosis later.
Evidence-based recommendations for optimal comanagement of patients with diabetes and bone loss, stresses the need to initiate treatment early.
In diabetes, poor glucose control may be a sign of hepatitis C.
Therapeutic identification and treatment of the hepatitis C virus may address otherwise unexplained and erradic changes in blood glucose, improving management in people with type 2 diabetes.
The way physicians order thyroid labs is highly variable.
Ordering the appropriate thyroid panel is wrong 30% of the time, and the right tests are missed equally as often, prompting discussion of need for clearer guidelines, and reliance on individualized care, in the meantime.
Significant variation was found in thyroid testing practices, suggesting a possible need for better guidelines to improve consistency.
Metformin doesn't provide cardiovascular benefits for people with diabetes.
While metformin didn't reduce the risk of atherosclerosis in people with type 1 diabetes as anticipated, secondary outcomes offered more promise, according to findings from the REMOVAL trial.
Levothyroxine Ineffective as treatment for Subclinical Hypothyroidism in seniors
Thyroid replacement therapy lowered thyrotropin levels in elderly patients, but treatment did not relieve any symptoms of hypothyroidism.
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