Endocrine Research Updates

For Medical Professionals

Patients with polycystic ovary syndrome need earlier screenings and follow-up.
The International PCOS Network cites need for screening for polycystic ovary syndrome in adolescent girls to improve long-term outcomes including diabetes, depression, and cardiovascular disease
Longer use FreeStyle Libre sensor approved; new diabetes drugs on the horizon.
Food and Drug Administration recognized potential for a variety of clinical advances in diabetes care including approval of 14-day use of Freestyle Libre CGM sensor, IND trial of new drug to improve vision in severe diabetic retinopathy, and NDA to market nasal glucagon for hypoglycemia rescue.
Less drastic treatments for most thyroid tumors offer same outcomes as surgery.
Further evidence suggests need for reevaluation of treatment for most thyroid nodules, challenging the preference for total thyroidectomy over lobectomy or active surveillance in thyroid cancer.
Active surveillance should be presented as an objective option over surgery.
A discussion protocol that prompts shared decision making based on objective treatment considerations of asymptomatic, small papillary thyroid tumors makes room for active surveillance over total thyroidectomy.
Lifestyle including diet and body weight are key to preventing diabetes.
Women with a history of gestational diabetes who are poor metabolizers of branched-chain amino acids might develop type 2 diabetes at a greater rate later in life.
Acromegaly requires early and effective treatment to restore quality of life;
When surgery is not pursued as first-line therapy, medication selection is critical to address risk of diabetes, hypertension, and cardiovascular disease to assure best long-term management.
Monitoring patients for signs hypparaothryoidism following thyroid surgery.
American Thyroid Association Statement offers recommendations for clinical management of hypoparathyroidism following thyroid surgery.
FDA grants orphan drug status to thyroid cancer and hypoparathyroidism.
Next generation tubeless Omnipod DASH Insulin Management System coming to market, a novel nasal spray product for diabetes gastoparesis is under review., and orphan drug status granted for treatment of hypoparathyroidism and anaplastic thyroid cancer..
Cushing's syndrome and Cushing's disease requires multimodal care.
Results of two systematic reviews indicate that while surgery is the preferred treatment, many patients present with contraindications without an accepted management paradigm leaving clinicians to follow a patient-centric approach to care.
Several novel diabetes management devices and technolgoy advances are approaching FDA review including first of its kind all-in-one patch, a much anticipated insulin capsule, and a shelf-stable glucagon rescue pen for severe hypoglycemia.
Symptoms of Hashimoto's disease are worsened in women with PCOS.
Hashimoto's disease (autoimmune thyroiditis) worsens reproductive and metabolic outcomes in patients with polycystic ovary syndrome.
wearable devices, glucose devices, diabetes technology
Brief highlights on prescription medication rating tool, reimbursement for use of wearable health tracking devices and an assessment of the health technology field.
Hormone replacement for low testosterone requires a proper diagnosis.
Addressing an age-related decline in serum testosterone is not clinically advisable whereas hypogonadism necessitates appropriately diagnosed medical intervention.
The best treatment for people with obesity and diabetes is bariatric surgery.
Given the surging rates of diabetes, hypertension, cardiovascular disease, and obesity-related cancers, the time has arrived for clinicians to address bariatric surgery as an appropriate option for many patients.
Risk of autoimmune diseases, such as diabetes, increased by Epstein-Barr virus.
Researchers uncover genetic link involving b cells that suggest an increased risk of developing at least seven identified autoimmune disorders, including type 1 diabetes, following a person's infection with the Epstein-Barr virus.
Researchers find underlying cause of treatment failure for standard BP care.
Researchers uncovered excess aldosterone as cause of antihypertensive treatment failure, and shed light on mechanisms to support breakthrough treatment success in resistant hypertension.
Breakthrough in understanding of resistant hypertension points to hormone imbalance as the reason for failure to respond to standard blood pressure treatment.
Women with PCOS may have hypothryoidism which have implications for pregnancy.
Women with polycystic ovary syndrome appear at increased risk for comorbid thyroid disorders, yet a study by researchers from the Cleveland Clinic introduced more questions about pregnancy outcomes.
Diabetes care is now achieving Integrated Continuous Glucose Monitoring.
A round-up of recent diabetes products and updated innovations and indications considered by the Food and Drug Administration, highlighting the first integrated CGM and first implantable glucose sensor.
Seeking new biomarker to identify greater diabetes risk for heart disease.
Evaluating a possible role for FGF-23 in CHD, accounting for differences in race, sex, and chronic kidney disease status from a subset of the REGARDS data
Evaluating a possible role for fibroblast growth factor-23 in CHD, accounting for differences in race, sex, and chronic kidney disease status from a subset of the REGARDS data
Innovations in diabetes care explode with 3 new diabetes products introduced.
March brings 3 diabetes product innovations, a clinician office task organizer app, and a warning about patient perceptions regarding attatins: they don't need them.