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Other Endocrine Disorders Research Updates

For Medical Professionals

Body composition and biomarkers of cardiovascular risk are affected by both growth hormone excess and growth hormone deficiency (GHD). While that is a known fact, it’s unknown how developing growth hormone deficiency after being treated for acromegaly affects body composition and cardiovascular risks. A study published in 2012 examined this.
Insulin resistance (IR) is associated with polycystic ovary syndrome (PCOS), which is a reproductive and metabolic disorder.
Treating acromegaly usually involves using somatostatin analogs (SA); these have been used for more than 25 years. However, there is a major disadvantage to using SA: a patient will need to continue the therapy indefinitely.
Diagnosing growth hormone deficiency (commonly abbreviated as GHD) in childhood is difficult. This is mostly because there are no true gold standards for diagnosis.
Researchers studied the cortisol awakening response in patients with shoulder and neck pain and in patients with fibromyalgia.
The objective of a study was to identify the optimal adrenal venous sampling (AVS) lateralization ratio for unilateral primary aldosteronism.
Children with congenital adrenal hyperplasia require a knowledgeable caregiver to help them in times of adrenal crisis and acute illness.
A study was done to examine the incidence of diabetes during growth hormone replacement therapy (GHRT).
Researchers from Germany looked at the clinical parameters that predict hypertension resolution following laparascopic adrenalectomy.
There are several treatment options for patients with acromegaly. A recent study looked at two treatments in particular: octreotide-lar (Oct-LAR) and surgery. The researchers wanted to see how well the treatments worked when compared to each other.
An article published in the Expert Opinion on Pharmacotherapy journal reviewed treatments of aggressive pituitary tumors. Reviewed surgery, pharmacotherapies, and radiotherapy.
Research was presented at the 2011 Endocrine Society Annual Meeting on using salivary cortisol for diagnosing hypercortisolism and hypocortisolism.
Low testosterone levels are associated with increased mortality in men, and men with type 2 diabetes have a high prevalence of testosterone deficiency.
Long-term safety and efficacy data on pediatric patients treated with Norditropin® are being collected through a registry called American Norditropin Studies: Web-Enabled Research.
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