Other Endocrine Disorders Research Updates

For Medical Professionals

A study that looks specifically at children who had treatment with recombinant growth hormone in France, and it evaluates the long-term mortality of those children.
Body composition and biomarkers of cardiovascular risk are affected by both growth hormone excess and growth hormone deficiency (GHD). While that is a known fact, it’s unknown how developing growth hormone deficiency after being treated for acromegaly affects body composition and cardiovascular risks. A study published in 2012 examined this.
Even though it’s known that growth hormone insulin-like growth factor-1 is key in normal brain growth, less is known about how the brain structure is impacted by growth hormone deficiency. A study examined this.
Does experiencing very stressful events early on in life change the way your body responds to stress? Read about how cortisol response and other stress axis reactions can change.
Congenital adrenal hyperplasia (CAH), a genetic adrenal disorder, was studied in Great Britain. Researchers wanted to make an estimate of the incidence of clinically-diagnosed CAH.
Insulin resistance (IR) is associated with polycystic ovary syndrome (PCOS), which is a reproductive and metabolic disorder.
Treating acromegaly usually involves using somatostatin analogs (SA); these have been used for more than 25 years. However, there is a major disadvantage to using SA: a patient will need to continue the therapy indefinitely.
Diagnosing growth hormone deficiency (commonly abbreviated as GHD) in childhood is difficult. This is mostly because there are no true gold standards for diagnosis.
Researchers studied the cortisol awakening response in patients with shoulder and neck pain and in patients with fibromyalgia.
The objective of a study was to identify the optimal adrenal venous sampling (AVS) lateralization ratio for unilateral primary aldosteronism.
Researchers looked at the effects that variations in thyroid function within the normal range have on both metabolic function and body composition.
Children with congenital adrenal hyperplasia require a knowledgeable caregiver to help them in times of adrenal crisis and acute illness.
A study was done to examine the incidence of diabetes during growth hormone replacement therapy (GHRT).
Researchers from Germany looked at the clinical parameters that predict hypertension resolution following laparascopic adrenalectomy.
There are several treatment options for patients with acromegaly. A recent study looked at two treatments in particular: octreotide-lar (Oct-LAR) and surgery. The researchers wanted to see how well the treatments worked when compared to each other.
Researchers examined two diagnostic tests for Cushing’s disease: the corticotropin-releasing hormone (hCRH) and desmopressin (DDAVP) tests.
An article published in the Expert Opinion on Pharmacotherapy journal reviewed treatments of aggressive pituitary tumors. Reviewed surgery, pharmacotherapies, and radiotherapy.
Research was presented at the 2011 Endocrine Society Annual Meeting on using salivary cortisol for diagnosing hypercortisolism and hypocortisolism.
Low testosterone levels are associated with increased mortality in men, and men with type 2 diabetes have a high prevalence of testosterone deficiency.
Long-term safety and efficacy data on pediatric patients treated with Norditropin® are being collected through a registry called American Norditropin Studies: Web-Enabled Research.