Thyroid cancer Research Updates

For Medical Professionals

The ThyroSeq v2.1 multigene next generation sequencing test showed a high sensitivity and specificity in the detection of cancer in thyroid nodules with atypia of undetermined significance/follicular lesion of undermined significance (AUS/FLUS) cytology.
New findings from a large prospective cohort add support to the hypothesis that moderate alcohol consumption may lower the risk of papillary and follicular thyroid carcinomas.
Findings suggest that Cyto-I/GEC-B nodules shows comparable clinical behavior to cytologically benign nodules and may be conservatively monitored.
Most information and support needs among survivors of thyroid cancer are unmet, according to a large online survey reported in the June issue of Thyroid. Key opinion leaders comment on the Morley-Goldfarb study.
Repeat fine-needle aspiration following a nondiagnostic result detected malignancy in less than 1% of cases, according to findings reported in the September issue of Radiology. The authors suggest that ultrasound followup may be more appropriate than repeat fine-needle aspiration in patients with initially nondiagnostic results from thyroid nodule biopsy.
A link between autoimmune thyroiditis and differentiated thyroid cancer was found in a surgical series of patients undergoing thyroidectomy but not in a cytological series of patients who underwent fine-needle aspiration, according to findings from a retrospective study published in the September issue of the Journal of Clinical Endocrinology and Metabolism.
EndocrineWeb spoke with Dr. Richard Kloos about the incidence of thyroid nodules and the role of gene expression classifiers. The interview was timely considering that during The Endocrine Society’s annual meeting the American Thyroid Association’s (ATA) preliminary guidelines regarding the management of thyroid nodules were announced.
Research suggests that women diagnosed with differentiated thyroid cancer during pregnancy or soon after are at significantly increased risk for tumor persistence or recurrence compared to women diagnosed when they are not pregnant.
Despite the increasing rates, the death rate from thyroid cancer has remained stable at 0.5 deaths per 100,000 people. The authors suggested that the increasing rates of thyroid cancer may be due to an increase in the detection of subclinical papillary thyroid cancers, which are unlikely to affect patients’ overall health.
Research presented at the 81st Annual Meeting of the American Thyroid Association notes an effective way to monitor differentiated thyroid cancer for recurrence.
Ectopic thyroid cancer is rare, but a study looked at the PubMed database for ectopic thyroid cancer articles from 1960 to 2011.
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