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Endocrinology News and Research Articles

Scientists explore how thyroid cancer metastasizes, often staying dormant for years
05/22/2011 - Distant metastases of thyroid cancer can dramatically reduce a patient's likelihood of survival, which is one reason why a scientist at the Ohio State University College of Medicine recently reviewed the current clinical understanding of how thyroid carcinoma cells migrate.
Researchers calculate the cost of osteoporosis-related hip fractures among elderly care residents
05/19/2011 - While the number of osteoporosis-related fractures that occur in a year is relatively well known, the direct cost of these injuries is rarely quantified, which is why a group of UK scientists recently attempted to do just that.
Common type 2 diabetes medication may raise risk of bladder cancer
05/19/2011 - The type 2 diabetes medication pioglitazone may be associated with an increased risk of bladder cancer, according to a new review of Food and Drug Administration data conducted by a team of Italian researchers.
Macrocephaly points to likelihood of PTEN mutation in follicular thyroid cancer patients
05/19/2011 - Among people with a mutation of a particular gene called PTEN, the rate of differentiated thyroid cancer (DTC) is between 3 and 10 percent, but until recently, researchers had not tabulated how many patients with follicular thyroid cancer (FTC) typically display the mutation.
Morbid obesity reduces the effectiveness of levothyroxine for patients with hypothyroidism
05/18/2011 - Due to the dampening effect that a higher body mass index (BMI) can have on the body's absorption of a thyroid hormone replacement called levothyroxine (LT4), a group of Greek researchers recently investigated how morbid obesity might change the uptake of this drug in patients with hypothyroidism.
Uncovering process that determines fate of stem cells may lead to better treatments for type 1 diabetes
05/18/2011 - By looking at markers on proteins known as histones, around which DNA molecules wind, a team of researchers from the University of Pennsylvania believes that it may be possible to predict the fate of embryonic stem cells. This knowledge could be used to steer these cells toward developing into insulin-producing pancreatic cells, which individuals with type 1 diabetes lack.
Men with type 2 diabetes are more likely to suffer cardiovascular complications than women
05/18/2011 - Type 2 diabetes is known to increase an individual's risk of developing cardiovascular complications, but a new study from a group of Yale University researchers shows that men are at significantly greater risk than women.
Excessive weight gain during pregnancy is tied to increased risk of metabolic problems like obesity and type 2 diabetes
05/17/2011 - Gaining too much weight during pregnancy can dramatically increase a woman's odds of becoming obese later in life and developing associated health problems, which often include type 2 diabetes, according to a new study from a team of British researchers.
Osteoporosis medications reduce risk of death in women
05/17/2011 - Due to the increased risk of death associated with osteoporosis, researchers from Australia's Garvan Institute of Medical Research and the University of New South Wales recently analyzed the effect that medications for bone loss have on longevity.
Studies summarize promising innovations in molecular diagnosis of thyroid cancer
05/17/2011 - Two recently released studies, one written by a pair of Greek endocrinologists and the other by an American pathologist, summarize the latest advancements made into the molecular analysis and diagnosis of thyroid cancer.
Enzyme may increase insulin resistance and type 2 diabetes risk
05/16/2011 - Higher levels of an enzyme known as PKC-delta may lead to greater insulin resistance and a higher risk of developing type 2 diabetes, according to a new study from the Joslin Diabetes Center. Researchers said that their findings may lead to the development of new medications that improve insulin sensitivity.
Limiting cholesterol levels may minimize inflammation and reduce type 2 diabetes risk
05/16/2011 - By stimulating the enzyme CEH to remove more cholesterol from cells, it may be possible to limit inflammation, improve insulin sensitivity and reduce an individual's type 2 diabetes risk, said a group of researchers from Virginia Commonwealth University School of Medicine.
Canadian osteoporosis-related hip fracture rates drop, yet remain significant
05/16/2011 - Due to the negative impact osteoporosis-related hip fractures can have on mobility and quality of life, a team of Canadian researchers recently set out to estimate the risk of such an injury among people age 50 and older.
Researchers assess causes of death among those who succumb to well-differentiated thyroid cancer
05/15/2011 - While well-differentiated thyroid cancer (WDTC) tends to have a high post-surgical survival rate, individuals who have been treated for this form of thyroid disease occasionally die nonetheless, and a team of New York researchers recently attempted to determine the reasons why.
Gender, primary language affect knowledge of osteoporosis
05/15/2011 - Researchers from Canada and the U.S. recently tested the knowledge of osteoporosis among fracture patients, and what they found is that many men and people who spoke English as a second language (ESL) were less likely to have an adequate understanding of progressive bone loss.
Researchers identify single gene that controls many risk factors for type 2 diabetes
05/15/2011 - A team of British researchers has found that the KLF14 gene, which was already known to play a role in the development of type 2 diabetes and high cholesterol levels, may serve a much broader purpose in the body, regulating many metabolic functions.
Low bone mineral density increases risks of heart attacks, as well as osteoporosis
05/12/2011 - It is commonly accepted that having a low bone mineral density (BMD) increases the likelihood of osteoporosis, but new research indicates that this skeletal deficiency can also boost the risk of heart attacks for both genders.
New study finds link between growth hormone therapy and type 2 diabetes in children
05/12/2011 - In recent years, prescribing growth hormone has become a common treatment for many childhood conditions. However, a new study from the pharmaceutical company Eli Lilly has found that this therapy may dramatically increase young people's risk of developing type 2 diabetes.
Genetic changes in thyroid cancer block vitamin D3 absorption in tumor cells
05/11/2011 - A recent letter to the editor of the journal Thyroid commented on the apparent connection between papillary thyroid cancer (PTC) and the overexpression of the CYP24A1 gene, which codes for enzymes that deactivate vitamin D3.
Researchers identify genetic pathway involved in fat storage that may predispose individuals to type 2 diabetes
05/11/2011 - The discovery of a new genetic pathway that controls the storage of energy as fat and its subsequent expenditure could lead to the development of new medications aimed at treating metabolic conditions like obesity and type 2 diabetes, says a group of researchers from the Salk Institute for Biological Studies.
Blocking a set of enzymes in the liver may turn off glucose production, leading to healthier blood sugar levels for type 2 diabetics
05/11/2011 - A new study from researchers at the Salk Institute for Biological Studies has shown that a group of enzymes known as histone deacetylases (HDACs) may play a key role in regulating the liver's production of glucose. The finding could lead to the development of new medications that allow individuals with type 2 diabetes to maintain tighter control over their blood sugar levels.
Osteoporosis treatment is less common among people with dementia
05/11/2011 - A study conducted by Swedish scientists has concluded that among elderly people with osteoporosis, those who suffer from dementia are less likely than their peers to receive treatments for progressive bone loss.
Researchers say type 2 diabetes may actually be an autoimmune disease
05/10/2011 - A new study from a group of Stanford University researchers suggests that, similar to type 1 diabetes, type 2 diabetes may be an autoimmune disorder. The classification of the disease as such could drastically change the way that doctors and scientists think about it, which may lead to the development of different treatments and medications.
New study links reliance on car to obesity, with implications for type 2 diabetes
05/10/2011 - The surging obesity rates and the increasing prevalence of type 2 diabetes may be closely associated with Americans' growing reliance on automobiles, suggests a new study out of the University of Illinois.
Study examines occult medullary thyroid cancer
05/10/2011 - Medullary thyroid cancer (MTC) is a relatively rare form of thyroid disease, one that is often difficult to detect, which is one reason why scientists at the Johns Hopkins University School of Medicine recently attempted to quantify the rate at which MTC goes undiscovered until a thyroidectomy.

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