Antioxidants found to mediate type 2 diabetes risk

Two natural compounds have been shown to prevent insulin resistance and inflammation in human tissue, which may reduce the risk of type 2 diabetes, according to a new study from Boston University researchers.

After treating human fat tissue with the antioxidants resveratrol and quercetin, the researchers then exposed the tissue to conditions that would normally lead to insulin resistance and inflammation. However, this tissue showed fewer signs of these conditions than would normally be expected.

The one issue with the study is that researchers treated the tissue with much higher levels of the antioxidants than is generally found in the human body. Resveratrol and quercetin are metabolized by the body into other compounds before it has a chance to reach fat tissue. Therefore, food and supplement sources of these nutrients may not be an effective way to reduce type 2 diabetes risk.

However, the findings do leave the door open for the development of future therapies that work along the same mechanisms. The researchers said that further studies should be conducted to see if their findings can be turned into a valid treatment for reducing type 2 diabetes risk.

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