Insulin-producing cells stop replicating after age 30

Type 2 diabetes is significantly more common among older individuals. New research suggests that this may be because insulin-producing cells in the body stop replicating in people around their 30th year.

The findings have major implications for the future of diabetes research. Currently, scientists are working towards developing treatment strategies that involve using stem cells to get the body to create more beta cells, which are responsible for producing insulin.

However, the researchers point out that their findings indicate this strategy could potentially fail because creating more beta cells is not something that the adult body does naturally.

The findings also provide valuable insights into why type 2 diabetes is so common among obese individuals. Larger bodies need more insulin to control blood sugar levels. However, if an individual put on weight after they stopped producing beta cells, they will likely not produce enough insulin to manage blood sugar levels.

"We found that beta cells turnover up to about age 30, and there they remain throughout life," said Bruce Buchholz, who led the study. "The body doesn't make new ones in adulthood and there might not be enough cells to control blood sugar."
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