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Biguanides for Type 2 Diabetes

Diabetes medication that prevents the liver from making more glucose

Biguanides are another medication class used to treat type 2 diabetes.

How they work: Biguanides affect the liver—not the pancreas like sulfonylureas, repaglinide, and nateglinide. They keep the liver from making more glucose when you don’t need it, thereby keeping your blood glucose level in a better range.
Special notes: Biguanides seem to make you less hungry, so it may help you lose weight. They may cause stomach upset, so take it with meals.
Example of biguanides:
  • Metformin (Glucophage) is a biguanide.


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