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Hashimoto's without anti-microsomal antibody (TPO)?

From: Gail2016 - 2 years 17 weeks ago

In a case study i am currently studying, a 47-year old woman with menstrual irregularities vs the other months, have symptoms and lab results that points to a primary hypothyroidism, such as, diffuse goiter, perioribital puffiness, difficulty in swallowing, increased TSH but low Free T4, Free T3, and total T4 and T3 uptake is also low.
However, anti-microsomal (TPO) antibodies is negative. Can this be diagnosed with Hashimoto's Thyroiditis without the presence of antibodies?

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