Factors That Predict Glycemic Control in Children
Age, Gender, and Disease Duration
A team led by researchers at Assiut University in Egypt set out to answer this question in a study. Titled, “Predictors of glycemic control in children with type 1 diabetes mellitus in Assiut-Egypt,” the study was published in September 2012 in the Indian Journal of Endocrinology and Metabolism.
The researchers examined data on 415 children between the ages of 2 and 18. All of the children had been living with type 1 diabetes for at least 1 year. The researchers collected data on the children’s medical histories and demographic factors. Other variables of interest included participants’ body mass indexes and HbA1c levels. Children who had HbA1c levels that were higher than those recommended by the American Diabetes Association were classified as having poor glycemic control.
The results showed that 190 out of the 415 children (45.8%) had poor glycemic control. Older children were more likely to have problems with glycemic control. Girls above the age of 14 had poorer glycemic control than boys in that age group.
Additionally, the longer children had been living with the disease and the older they were at the onset of T1DM, the worse their control. Children who had poor glycemic control also had higher average cholesterol levels and triglycerides than children who had good glycemic control.
The study authors state that their findings held even after they controlled for confounding factors. Older children who lived with T1DM for more than 5 years, and children with high triglyceride levels, were more likely to have poor glycemic control. The researchers state that pediatricians should be aware of these factors so that they may target interventions to help children manage T1DM.