Kidney damage may increase the mortality rate of type 1 diabetes patients

According to researchers at the University of Pittsburgh Graduate School of Public Health, type 1 diabetes patients who have early and asymptomatic kidney damage may have a higher rate of mortality.

The team looked at data from 658 men and women who had enrolled in the Pittsburgh Epidemiology of Diabetes Complications Study. The long-term examination started in 1986 and has been following these individuals, who were all diagnosed with childhood onset diabetes. Researchers tested their levels of the albumin protein, which indicates kidney damage when it accumulates in urine.

A total of 152 participants died from kidney damage within 20 years of the study, a rate that is 6.2 percent higher than that of age- and sex-matched individuals in the general population. The researchers found that type 1 diabetics who had normal kidneys did not have significantly different mortality rates from that of control individuals.



"Early stages of kidney disease in type 1 diabetes may be very important because they can lead to a sizable increase in the risk of death," said lead investigator Aaron M. Secrest. "The hopeful news is that this risk virtually disappears when kidneys remain healthy, which should encourage physicians to closely monitor kidney health in people with type 1 diabetes."ADNFCR-3583-ID-19934708-ADNFCR

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