My brother had Graves disease about 6 years ago. He had his thyroid removed and has been on replacement therapy. We lives far away and we are not very close but did have a nice visit together a few months ago. Then a couple of days ago he lashed out on me on the phone and it made no sense at all. When I spoke to our mom, she had contacted him to see what was going on. When they spoke he also went on about stories from growing up that didn't make any sense and were completely twisted. We were able to contact someone who sees him regularly and they only noticed weight gain. Our mother contacted his doctor (sports medicine doc not endocrinologist) but they only said his levels were normal (4 months ago) and he is on Levothyroxine. I spoke with him again and the stories are completely false, not to mention the explanations are completely unorganized. He is worried we think he is crazy & won't consider that he might be hypothyroid. Any advice?