Daniel J. Toft MD, PhD

Endocrinologist
Northwestern University
Chicago, IL

About Daniel J. Toft MD, PhD

Daniel Toft, MD, PhD, is an instructor at Northwestern University in Chicago. He completed his undergraduate education at Brown University before earning his medical degree at the Northwestern University Feinberg School of Medicine. He also earned his PhD from Northwestern, where his research focused on hormones in pregnancy and disease. Currently he is engaged in translational breast cancer research. He has a general endocrinology practice; however, he is especially interested in bone health, adrenal disease, and thyroid disease.

Publications

 

Publications
Albert M, Gao Y-M, Toft D, Lee W, Wold A. Photoassisted gold deposition on TiO2 powder. Materials Research Bulletin 27:961-6. 1992.

Ajtai K, Ilich PJ, Ringler A, Sedarous SS, Toft DJ, Burghardt TP. Stereospecific reaction of muscle fiber proteins with the 5' or 6' isomer of (iodoacetamido) tetramethylrhodamine. Biochemistry 31:12431-40. 1992.

Ajtai K, Toft DJ, Burghardt TP. Path and extent of cross-bridge rotation during muscle contraction. Biochemistry 33:5382-91. 1994.

Toft DJ, Linzer DIH. Characterization of novel members of the prolactin/growth hormone family. The Endocrine Society 81st Annual Meeting. (abstract) 1999.

Toft DJ, Linzer DI. Prolactin (PRL)-like protein J, a novel member of the PRL/growth hormone family, is exclusively expressed in maternal decidua. Endocrinology 140:5095-101. 1999.
 

Lin J, Toft DJ, Bengtson NW, Linzer DI. Placental prolactins and the physiology of pregnancy. Recent Progress in Hormone Research 55:37-51; discussion 52. 2000.

Toft DJ, Linzer DI. Identification of three prolactin-related hormones as markers of invasive trophoblasts in the rat. Biology of Reproduction 63:519-25. 2000.

Toft DJ, Rosenberg SB, Bergers G, Volpert O, Linzer DI. Reactivation of proliferin gene expression is associated with increased angiogenesis in a cell culture model of fibrosarcoma tumor progression. Proceedings of the National Academy of Sciences of the United States of America 98:13055-9. 2001.

Layden BT, Dubner S, Toft DJ, Kopp P, Grimm S, Molitch ME. Primary CNS lymphoma with bilateral symmetric hypothalamic lesions presenting with panhypopituitarism and diabetes insipidus. Pituitary 3 Jan 2009 (Epub ahead of print).

Articles Written by Daniel J. Toft MD, PhD

Addison’s Disease and Adrenal Insufficiency Overview
Addison’s disease, a rare disorder, develops when the adrenal glands do not produce enough of the hormone cortisol. Sometimes, the adrenal glands also don’t produce enough of the aldosterone hormone. Includes list of Addison’s disease symptoms.
Growth Hormone Therapy
Find out the basics of growth hormone therapy, the most common treatment for growth hormone deficiency, in this article.
Acromegaly Causes
Acromegaly, a growth hormone disorder, is always caused by a benign (non-cancerous) tumor, usually one on the pituitary gland. These tumors are also called adenomas, and they cause the body to produce too much growth hormone.
Acromegaly Diagnosis
To diagnose acromegaly (a growth hormone disorder), the doctor will probably do 3 things: look for physical changes, test your growth hormone and insulin-like growth factor-1 levels, and check for a tumor using imaging tests.
Acromegaly Overview
Acromegaly (called gigantism when it occurs in children) is a growth hormone disorder. It causes the pituitary gland to release too much growth hormone, leading to excessive growth.
Acromegaly Complications
If left untreated (or undertreated), acromegaly can lead to complications. Read about the most common complications from this growth hormone disorder.
Acromegaly Symptoms
The symptoms of acromegaly (a growth hormone disorder) develop gradually. Read this article to learn more.
Medications for Acromegaly
People with acromegaly have several medications they can try to treat this growth disorder. Medications are usually used after surgery if surgery doesn't lower growth hormone and insulin-like growth factor-1 levels. Includes side effects for each medication.
Acromegaly Surgery
Learn about the different procedures, risks, and goals for acromegaly surgery.
Cushing’s Syndrome Symptoms
In this article, learn about the classic symptoms of Cushing’s syndrome and also how they may differ for men and women.
Lowering Your Risk for Osteoporosis
While you can’t change some of your risk factors for osteoporosis, many others are well within your control.
Exercise Tips to Prevent Osteoporosis
Exercise is one of the best ways to help strengthen your bones and prevent osteoporosis. Learn about three types of exercise.
Dietary Tips for Osteoporosis Prevention
A healthy, balanced diet rich in calcium and vitamin D (which helps your body absorb calcium) can lower your chances of developing osteoporosis.
Patient Guide to Osteoporosis Prevention
This Patient Guide provides tips on eating right, exercising, and working with your doctor to protect your bones and prevent osteoporosis.
Turner Syndrome Overview
Turner syndrome is caused by the complete or partial lack of one of the female sex chromosomes. This results in a range of complications, including stunted growth and development, an increased risk of heart and kidney problems, and infertility.

Articles Reviewed by Daniel J. Toft MD, PhD

Osteoporosis Symptoms
Osteoporosis is known as the silent disease because there are no apparent early symptoms. Often, a broken bone, a loss in height, or a hunched back provides the first indication that you have the disease.
Osteoporosis Overview
Osteoporosis is a disorder caused by a loss of bone density. When your bones become weak, they become prone to painful fractures. Osteoporosis affects millions of Americans—both men and women—but it is preventable with healthy lifestyle choices.
Cushing’s Syndrome Causes
Article explains common causes of Cushing’s syndrome, including pituitary tumors, adrenal tumors, and excessive production of cortisol. Also, learn how corticosteroids can cause Cushing’s syndrome.
4 Lifestyle Tips for Cushing’s Syndrome
Other than taking medications or having surgery, what else can you do to live well with Cushing’s syndrome? In this article, you’ll learn 4 easy lifestyle tips that can help you thrive with Cushing’s syndrome.
Cushing’s Syndrome Treatments
Find out about common treatments for Cushing’s syndrome, such as surgery, radiation, and medications.
Cushing’s Syndrome Diagnosis
To diagnose Cushing’s syndrome, your doctor will do a physical exam and ask you about your personal and family medical history. You may also need tests to confirm the diagnosis. Learn what common exams and tests doctors use to diagnose Cushing’s syndrome.
Osteoporosis Prevention
There are ways you can help prevent osteoporosis, such as exercise, eating a healthy diet rich in calcium and vitamin D, and cutting out smoking.
Turner Syndrome FAQ: Part 2
Part 2 of Turner syndrome's FAQ. Learn fast facts and get answers to your most common questions.
Turner Syndrome FAQ: Part 1
Get quick answers to the most common questions about Turner syndrome. Includes links to in-depth articles so that you can get more information.
Turner Syndrome Glossary
This article includes important terms and definitions associated with Turner syndrome to help you better understand this growth disorder.
Turner Syndrome Facts and Tips
This article includes a quick list of facts and tips about Turner syndrome-- from what it is to how it's treated. It is an easy-to-read resource as you learn about and live with this condition.
Growth Hormone Deficiency Diagnosis
Find out what exams and tests are commonly used to diagnose growth hormone deficiency.
5 Questions to Ask Your Doctor About Osteoporosis
Take this list of osteoporosis prevention questions with you to your next doctor’s appointment to stay one step ahead.
Risk Factors for Osteoporosis
Osteoporosis has many risk factors. Some are unavoidable—such as age or a family history of the disease. But there are some risk factors that you do have control over, including eating a nutrient-rich diet and being active.
Bracing: An Osteoporosis Treatment Option
Braces help treat osteoporosis-related spinal fractures. They are typically worn for a short period of time because they may prevent you from strengthening your bones. You may also wear a cast or splint if you have a simple wrist fracture.

Financial Disclosures for Daniel J. Toft MD, PhD

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Author's Statement

I, the undersigned, declare that neither I nor members of my immediate family have a financial interests or affiliation with commercial companies whose products and / or services may be mentioned in the materials I have authored, edited or reviewed for presentation on Vertical Health, LLC’s websites.
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